The Connection Between Actin ATPase and Polymerization
نویسندگان
چکیده
Remodeling of the actin filament system in cells results from strictly regulated polymerization and depolymerization of actin, where hydrolysis of actin‐bound ATP is crucial. Actin–actin interactions are influenced by the state of the bound nucleotide, and many microfilament regulators influence the actin ATPase by binding preferentially either to ATP/ADP Pi‐ or ADP‐bound actin. This chapter summarizes observations made concerning the actin ATPase and its role in the biological activity of actin and actin filaments.
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